All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions. One of the most well-studied cellular responses is how ...

Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

Every flu season, injectable vaccines prime the immune system to produce antibodies that circulate through the bloodstream.

Our work shows how high-affinity B cells can bank really advantageous mutations by essentially cloning themselves rather than continuing to mutate. Perhaps we will soon be able to tailor vaccines to ...